Hematology is the branch of medicine concerned with diseases of the blood in the broad sense:
- various types of anemia.
- myelodysplastic syndromes
- hemostatis disorders (disturbances) – hemorrhagic diseases (thrombocytopenia, hyperplasia, hemophilia, von Willebrand’s disease, hypercougulable states (inherited and acquired thrombophilias).
Phlebology is now emphasizing more and more genetic predisposition to thrombosis (inborn thrombophilias), so with risk factors or events suggesting us it ,it is worth being tested.
Indications for diagnosis of thrombophilis include:
- thrombosis during pregnancy
- thrombosis during contraception or in hormone replacement therapy
- recurrent thrombosis
- atypical localization, arterial thrombosis
- venous thrombosis with no identifiable cause before the age of 50
- miscarriage and a stillbirth
- heparin-induced thrombocytopenia.
The most common types of genetic tendency of thrombophilia are:
- V Leiden factor
- G20210A mutation in the prothrombin gene.
- heterozygous protein C deficiency
- heterozygous protein S deficiency
- heterozygous antithrombin deficiency
- increased factor VIII activity
- a combination of several factors often occurs.
The most common inherited type of thrombophilia is the anti-phospholipid group.